Editors' introduction: Vaccine safety throughout the product life cycle.

A Methodology for Product Performance Analysis under Effects of Multi-Physical Phenomena

Due to the development of science and technology, the computer has become a useful tool for supporting engineering activities in product design. Many computer aided tools such as CAD/CAM, product data management (PDM), product life cycle assessment (PLA), etc., have been popularly used in industry for reducing product development lead-time and increasing total product quality. However, the nume...

An EPQ Model for Product Life Cycle (Maturity Stage) with Deteriorating Items and Shortages

  A product life cycle is the life span of a product in which the period begins with the initial product specification and ends with the withdrawal from the market of both the product and its support. A product life cycle can be divided into several stages characterized by the revenue generated by the product. This study investigates inventory control policies in a manufacturing system for a si...

Guest Editors' Introduction: Test and the Product Life Cycle

Stability Study of Measles AIK-C Strain, Mumps RS-12 Strain and Rubella Takahashi Strain in MMR Vaccine

Stability studies play a critical role in assuring product quality at all points in the vaccine life cycle and havea major impact on the success of immunization programs worldwide. The purpose of stability study isdetermination of the vaccine quality under the variety of environmental factors and to establish a re-testperiod or a shelf life and recommended storage conditions. In this study thre...

Overview of the validation procedures for a vaccine production: from R&D level to the pre-qualification stage

Just like any other process, vaccine manufacturing procedures are defined as a series of interrelated functions and activities using a variety of specified actions and equipment designed to produce a defined product. To assure the reproducibility and consistency of such processes, they must be carried out using validated equipment and under the established procedures that meet all the acceptanc...